Manchester United suffered a double injury blow as Lisandro Martinez and Raphael Varane were withdrawn early against Sevilla.
Martinez had no one around him when he suddenly went down and was reduced to tears in the 2-2 Europa League quarter-final first-leg drawat Old Trafford.
His Argentina teammates, Marcos Acuna and Gonzalo Montiel of Sevilla, had to carry him off the pitch in the closing moments of the match.
And the stretcher had to come out at the sidelines for the defender, who could be seen with his head in his hands in a painful sight for United fans.
Varane was forced off at half-time with an injury and manager Erik ten Hag was not too confident when asked about the severity of both issues after the match.
“It doesn’t look that great,” he said of Martinez. “We have to wait, I can’t say in this moment. Same with Raphael Varane.
“I didn’t speak with him after the game but I know of an injury complain over the last weeks so we have to see how it is now.”
However, Ten Hag did stress an important detail and added: “I cannot tell what it is but it is not the Achilles. No that is not the area.”
The United boss added: “I think the injury [Martinez] will not play on Sunday.
“But again, I can’t say a realistic diagnosis and I prefer to wait. And then we are clear. We will know exactly what it is.”
Martinez’s injury also forced United to play with ten men for the last ten minutes of the match and it ended up being fatal.
The Red Devils raced into a two-goal lead after 21 minutes when Marcel Sabitzer became an unlikely hero.
But in the most extraordinary circumstances, United scored two own goals to allow Sevilla hope of going through.
A low cross from Jesus Navas was first diverted towards his own net by Tyrell Malacia with David de Gea not reacting quick enough before going in to make it 2-1.
And it went from bad to worse when a header going miles wide whacked off Harry Maguire, who came on for Varane, in the face, where it flew into the back of the net with just moments left.
Ten Hag will have a huge headache on his hands, as well, with Bruno Fernandes picking up a yellow card that rules him out of the tie.
With Marcus Rashford set to miss the match through injury and potentially Varane and Martinez as well, fans are understandably worried ahead of the second leg.
It’s not just the Europa League that will be cause for concern as the club is also trying to finish in the top of the Premier League and qualify for next season’s Champions League, while they have Brighton in the FA Cup semi-final, too.
“We’re genuinely in trouble,” one wrote on Twitter when looking at the injuries piling up that also includes Luke Shaw sidelined.
“It’s not looking good for the rest of the season,” another said, while one user is seeing the worst, writing: “Without Rashford, Martinez, Varane, Shaw and Bruno our season might really be over.”
A fourth said: “Not even bothered by the scoreline… but losing Martinez, Varane, Shaw and Rashford at this stage of the season… guess it’s over in some competitions.”